While the risk of HIV transmission is highest for those having anal sex, there are some other scenarios in which PrEP might be beneficial.
For example, if you have condomless vaginal sex, there is still some risk of HIV transmission from infected semen, pre-cum or vaginal fluids. PrEP would likely be of significant benefit to you if you are having vaginal sex with gay, bisexual, or other men who have sex with men outside of a monogamous/exclusive sexual relationship.
PrEP would also likely benefit:
- People having vaginal sex with partners who are living with HIV where the HIV-positive partner does not maintain an undetectable viral load.
- People intending to travel overseas and anticipating condomless vaginal sex with partners in regions of high HIV-prevalence.
If you are only engaging in oral sex, then you will likely not benefit from PrEP, as oral sex presents an extremely low risk of HIV transmission. Having an open and bleeding wound in your mouth does increase the risk of oral HIV transmission slightly, but there would need to be a significant amount of semen containing a high HIV viral load coming into direct contact with the wound. You cannot acquire or pass on HIV by rimming (licking or eating out someone's ass) and you cannot acquire HIV by receiving oral sex.
People who have shared needles in the past or anticipate sharing needles during injecting drug use in the future, especially in the context of chemsex, may also benefit from PrEP.